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Awards
Won 2 awards & 14 nominations
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Users' rating: 5.8

65 votes

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About the movie
Year
2001
Runtime
1 h 35 min
Genres
Animation, Action, Adventure, Comedy, Family, Fantasy
Country
United States
Writer
Plotline
A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.



Every third American is obese. Check if you are too!

Starring



Main cast

Chris Rock Osmosis Jones
William Shatner Mayor Phlegmming
Ron Howard Tom Colonic
Kid Rock Kidney Rock
Kenny Olson Kidney Rock
Jason Krause Kidney Rock
Joe C. Kidney Rock
Stefanie Eulinberg Kidney Rock
Jimmie Bones Kidney Rock
Uncle Kracker Kidney Rock
Jonathan Adams Additional Character Voice
Carlos Alazraqui Additional Character Voice
Keith Anthony Additional Character Voice




External critics' reviews

Chicago Tribune Robert K. Elder
Gets under your skin with laughs that are fast, slick and slippery and with visuals as vivid as anything this side of Demerol. more
Entertainment Weekly Lisa Schwarzbaum
Oscillates between streaky black comedy and sanitary instruction. more
Seattle Post-Intelligencer Sean Axmaker
Surprise of surprises, it's a blast. more
Village Voice Michael Atkinson
Resuscitates the filmgoing summer with a vital jolt of pure piss and vinegar. more
Los Angeles Times Jan Stuart
Warts and all, Osmosis Jones is the year's ultimate bodily functions comedy. more
Wall Street Journal Joe Morgenstern
A genuinely eccentric comedy that explodes with funny ideas and expresses most of them in wildly original animation.
Chicago Sun-Times Roger Ebert
Likely to entertain kids, who seem to like jokes about anatomical plumbing. For adults, there is the exuberance of the animation and the energy of the whole movie, which is just plain clever. more
Philadelphia Inquirer Carrie Rickey
Should you take the kids? Boys 8 to 11 are the target audience for this gross-out film. A better question might be, should they take the parents? more
Boston Globe Jay Carr
In a dismal summer for movies, Osmosis Jones is a fresh breath of foul air. more
The New York Times A.O. Scott
Often very smart about being silly. more


Show more external critic's reviews

External users' reviews

Amazon Schtinky "Schtinky"
Osmosis Jones is one of those movies you almost feel like you have to apologize for liking. Well, forget about it, because this is a very funny and downright entertaining movie with no class whatsoever! The scenes bounce between live acting and full animation, determined by whether we are outside or inside the body of Frank. The casting for this silly and peculiar movie was expertly chosen for both live and voice roles. Live, we have Bill Murray as Frank, in his most disgusting character since Caddyshack. Chris Elliot plays his brother Bob, and manages to challenge Murray in the... more
Amazon J. Hunt
I've been a 5th grade teacher for 5 years and have shown this movie each year as a reward after learning about the human body in science/health. The kids, for the most part, really enjoy it. There is just enough nasty stuff in there to gross them out - which they love! As a teacher, I just love the entire analogy of the story - every little cell in the body is working toward the same goal - keeping Frank alive. The kids like it, and I also enjoy it. There are some moments in there that are more adult humor that the kids don't even catch, so I'm able to get a laugh out of it. more
Amazon Ren Culpepper
Osmosis Jones is a really good movie, if a bit... well... disgusting at times. The plot revolves around a white blood cell named Osmosis Jones (voiced by Chris Rock) who serves as a police officer in the body of a guy named Frank (Bill Murray). When a dastardly virus named Thrax (voiced by Laurence Fishburne) invades Frank's body, it's up to the immunity force to stop him, and Ozzy is teamed up with a cold tablet named Drixobensomedaphedramine, or Drix for short (voiced by the always-wonderful David Hyde Pierce). Meanwhile, the pompous blood cell politician in charge of Frank's body, Mayor... more


Show more external user's reviews

See also

A human-looking, apparently unstoppable cyborg is sent from the future to kill Sarah Connor; Kyle Reese is sent to stop it.
Planet Spaceball's President Skroob sends Lord Dark Helmet to steal Planet Druidia's abundant supply of air to replenish their own, and only Lone Starr can stop them.
With personal crises and age weighing in on them, LAPD officers Riggs and Murtaugh must contend with a deadly Chinese crimelord trying to get his brother out of prison.

Series

The further adventures of Osmosis Jones and Drix as they defend the body of a young boy.


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